Study: Bird flu vaccine only works at highest dose

Reuters
Posted: March 31st, 2006 by Steve Trinward

“An experimental vaccine against H5N1 bird flu only appears to work at the very highest doses, meaning it will be harder than feared to protect the population against a pandemic, researchers said on Wednesday. The vaccine, made by a unit of Sanofi-Aventis and based on an H5N1 virus that killed a Vietnamese man in 2004, only produced a satisfactory immune response in volunteers at two doses of 90 micrograms each. That is 12 times what is needed for the annual seasonal flu shot. ‘It is a bit of muted good news in that we are going in the right direction, but the sobering news is we have a long way to go,’ National Institute of Allergy and Infectious Diseases Director Dr. Anthony Fauci said in a telephone briefing before the findings appeared in the New England Journal of Medicine. These findings mean there is only enough H5N1 vaccine now in the U.S. stockpile to protect about 4 million Americans in a pandemic, Fauci said.” [editor’s note: Another day, another bird flu scare-story?- SAT] (03/30/06)

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