Ascorbic acid competes with sugar in the immune system

News With Views
Posted: January 1st, 2007 by Steve Trinward
Author: Dr. James Howenstine, MD.

“Nearly every animal converts sugar into ascorbic acid (Vitamin C). Human beings, primates and guinea pigs are the only organisms unable to do this. The enzyme L-gulonolactone oxidase that accomplishes this chemical reaction does not work in these beings. This forces these beings to obtain ascorbic acid from food or supplements. Research studies suggest that humans would produce about 2 to 4 grams of Vitamin C daily under normal conditions and about 15 grams daily[1] when under stress. Insulin moves both glucose and ascorbic acid into cells including phagocytic immune cells. The phagocytic cells like leukocytes attack and remove microbes, tumor cells and debris from the blood. The level of ascorbic acid in leukocytes may be 80 times greater than that found in plasma. Glucose and ascorbic acid are constantly competing for insulin transport so diets high in sugar and carbohydrates will decrease the amount of ascorbic acid that enters cells and thus create undesirable effects on the immune response.” (12/25/06)

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